| Methamphetamine |
Cocaine |
| Man-made |
Plant-derived |
| Smoking produces a high that lasts 8-24 hours |
Smoking produces a high that lasts 20-30 minutes |
| 50% of the drug is removed from the body in 12 hours |
50% of the drug is removed from the body in 1 hour |
| Limited medical use |
Used as a local anesthetic in some surgical procedures |